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Schistosome Infection Stimulates Host CD4(+) T Helper Cell and B-Cell Responses against a Novel Egg Antigen, Thioredoxin Peroxidase

Egg granuloma formation during schistosome infections is mediated by CD4(+) T helper (Th) cells sensitized to egg antigens; however, most of the relevant sensitizing egg antigens are still unknown. Here we show that schistosome thioredoxin peroxidase (TPx)-1 is a novel T- and B-cell egg antigen in s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Williams, David L., Asahi, Hiroko, Botkin, Douglas J., Stadecker, Miguel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97995/
https://ncbi.nlm.nih.gov/pubmed/11160011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.1134-1141.2001
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