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Schistosome Infection Stimulates Host CD4(+) T Helper Cell and B-Cell Responses against a Novel Egg Antigen, Thioredoxin Peroxidase

Egg granuloma formation during schistosome infections is mediated by CD4(+) T helper (Th) cells sensitized to egg antigens; however, most of the relevant sensitizing egg antigens are still unknown. Here we show that schistosome thioredoxin peroxidase (TPx)-1 is a novel T- and B-cell egg antigen in s...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Williams, David L., Asahi, Hiroko, Botkin, Douglas J., Stadecker, Miguel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97995/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.2.1134-1141.2001
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