Immunomodulatory Effects of Anti-CD4 Antibody in Host Resistance against Infections and Tumors in Human CD4 Transgenic Mice

Anti-CD4 antibodies, which cause CD4(+) T-cell depletion, have been shown to increase susceptibility to infections in mice. Thus, development of anti-CD4 antibodies for clinical use raises potential concerns about suppression of host defense mechanisms against pathogens and tumors. The anti-human CD...

Popoln opis

Bibliografske podrobnosti

izdano v:	Infect Immun
Principais autores:	Herzyk, Danuta J., Gore, Elizabeth R., Polsky, Rodd, Nadwodny, Kimberly L., Maier, Curtis C., Liu, Susan, Hart, Timothy K., Harmsen, Allen G., Bugelski, Peter J.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2001
Teme:	Microbial Immunity and Vaccines
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97984/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.2.1032-1043.2001
Oznake:	Označite Brez oznak, prvi označite!