Safety and Immunogenicity of Increasing Doses of a Clostridium difficile Toxoid Vaccine Administered to Healthy Adults

Clostridium difficile is a major cause of nosocomial diarrhea in industrialized countries. Although most illnesses respond to available therapy, infection can increase morbidity, prolong hospitalization, and produce life-threatening colitis. Vaccines are being explored as an alternative means for pr...

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Autors principals: Kotloff, Karen L., Wasserman, Steven S., Losonsky, Genevieve A., Thomas, William, Nichols, Richard, Edelman, Robert, Bridwell, Margaret, Monath, Thomas P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97978/
https://ncbi.nlm.nih.gov/pubmed/11159994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.988-995.2001
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