Safety and Immunogenicity of Increasing Doses of a Clostridium difficile Toxoid Vaccine Administered to Healthy Adults

Clostridium difficile is a major cause of nosocomial diarrhea in industrialized countries. Although most illnesses respond to available therapy, infection can increase morbidity, prolong hospitalization, and produce life-threatening colitis. Vaccines are being explored as an alternative means for pr...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Kotloff, Karen L., Wasserman, Steven S., Losonsky, Genevieve A., Thomas, William, Nichols, Richard, Edelman, Robert, Bridwell, Margaret, Monath, Thomas P.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Microbial Immunity and Vaccines
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11159994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.2.988-995.2001
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