Vaccination with Calpain Induces a Th1-Biased Protective Immune Response against Schistosoma japonicum

A large subunit of calpain, a calcium-activated neutral proteinase, from Schistosoma japonicum was cloned and expressed in Escherichia coli. When BALB/c mice were immunized with purified recombinant calpain (r-calpain) emulsified in complete Freund's adjuvant, a significant reduction in the num...

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Detalhes bibliográficos
Main Authors: Zhang, Renli, Yoshida, Ayako, Kumagai, Takashi, Kawaguchi, Hitoshi, Maruyama, Haruhiko, Suzuki, Takashi, Itoh, Makoto, El-Malky, Mohamed, Ohta, Nobuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97894/
https://ncbi.nlm.nih.gov/pubmed/11119528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.386-391.2001
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