Vaccination with Calpain Induces a Th1-Biased Protective Immune Response against Schistosoma japonicum

A large subunit of calpain, a calcium-activated neutral proteinase, from Schistosoma japonicum was cloned and expressed in Escherichia coli. When BALB/c mice were immunized with purified recombinant calpain (r-calpain) emulsified in complete Freund's adjuvant, a significant reduction in the number o...

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Pubblicato in:	Infect Immun
Autori principali:	Zhang, Renli, Yoshida, Ayako, Kumagai, Takashi, Kawaguchi, Hitoshi, Maruyama, Haruhiko, Suzuki, Takashi, Itoh, Makoto, El-Malky, Mohamed, Ohta, Nobuo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97894/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11119528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.1.386-391.2001
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