Inactivation of the srtA Gene in Streptococcus gordonii Inhibits Cell Wall Anchoring of Surface Proteins and Decreases In Vitro and In Vivo Adhesion

The srtA gene product, SrtA, has been shown to be required for cell wall anchoring of protein A as well as virulence in the pathogenic bacterium Staphylococcus aureus. There are five major mechanisms for displaying proteins at the surface of gram-positive bacteria (P. Cossart and R. Jonquieres, Proc...

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Bibliographic Details
Main Authors: Bolken, Tové C., Franke, Christine A., Jones, Kevin F., Zeller, Gloria O., Jones, C. Hal, Dutton, Emma K., Hruby, Dennis E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97857/
https://ncbi.nlm.nih.gov/pubmed/11119491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.75-80.2001
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