Interleukin 12 as an Adjuvant to WI-1 Adhesin Immunization Augments Delayed-Type Hypersensitivity, Shifts the Subclass Distribution of Immunoglobulin G Antibodies, and Enhances Protective Immunity to Blastomyces dermatitidis Infection

Cell-mediated immunity is pivotal in host resistance to Blastomyces dermatitidis infection. Immunization of mice with the WI-1 adhesin enhances resistance against experimental pulmonary infection but elicits features of a mixed T-helper-cell immune response. Immune mice acquire delayed-type hypersen...

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Pubblicato in:	Infect Immun
Autori principali:	Wüthrich, Marcel, Finkel-Jiminez, Beatriz E., Klein, Bruce S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.12.7172-7174.2000
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