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Interleukin 12 as an Adjuvant to WI-1 Adhesin Immunization Augments Delayed-Type Hypersensitivity, Shifts the Subclass Distribution of Immunoglobulin G Antibodies, and Enhances Protective Immunity to Blastomyces dermatitidis Infection
Cell-mediated immunity is pivotal in host resistance to Blastomyces dermatitidis infection. Immunization of mice with the WI-1 adhesin enhances resistance against experimental pulmonary infection but elicits features of a mixed T-helper-cell immune response. Immune mice acquire delayed-type hypersen...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC97835/ https://ncbi.nlm.nih.gov/pubmed/11083850 |
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