Expression of the Nitric Oxide Synthase 2 Gene Is Not Essential for Early Control of Mycobacterium tuberculosis in the Murine Lung

The interleukin-12 and gamma interferon (IFN-γ) pathway of macrophage activation plays a pivotal role in controlling tuberculosis. In the murine model, the generation of supplementary nitric oxide by the induction of the nitric oxide synthase 2 (NOS2) gene product is considered the principal antimic...

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Vydáno v:	Infect Immun
Hlavní autoři:	Cooper, Andrea M., Pearl, John E., Brooks, Jason V., Ehlers, Stefan, Orme, Ian M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Host Response and Inflammation
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.12.6879-6882.2000
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