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Key Role for DsbA in Cell-to-Cell Spread of Shigella flexneri, Permitting Secretion of Ipa Proteins into Interepithelial Protrusions

DsbA, a disulfide bond catalyst, is necessary for realization of the pathogenic potential of Shigella flexneri. Sh42, a mutant strain differing from wild-type M90TS solely because it expresses nonfunctional DsbA33G (substitution for 33C at the active site), secreted less IpaB and IpaC than M90TS in...

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Bibliografski detalji
Glavni autori: Yu, Jun, Edwards-Jones, Bryn, Neyrolles, Olivier, Kroll, J. Simon
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97732/
https://ncbi.nlm.nih.gov/pubmed/11035758
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