The Collagen-Binding Adhesin Is a Virulence Factor in Staphylococcus aureus Keratitis

A collagen-binding strain of Staphylococcus aureus produced suppurative inflammation in a rabbit model of soft contact lens-associated bacterial keratitis more often than its collagen-binding-negative isogenic mutant. Reintroduction of the cna gene on a multicopy plasmid into the mutant helped it re...

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Pubblicato in:	Infect Immun
Autori principali:	Rhem, Marcus N., Lech, Elizabeth M., Patti, Joseph M., McDevitt, Damien, Höök, Magnus, Jones, Dan B., Wilhelmus, Kirk R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Molecular and Cellular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97678/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10816547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.6.3776-3779.2000
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