The Collagen-Binding Adhesin Is a Virulence Factor in Staphylococcus aureus Keratitis

A collagen-binding strain of Staphylococcus aureus produced suppurative inflammation in a rabbit model of soft contact lens-associated bacterial keratitis more often than its collagen-binding-negative isogenic mutant. Reintroduction of the cna gene on a multicopy plasmid into the mutant helped it re...

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Bibliographic Details
Main Authors: Rhem, Marcus N., Lech, Elizabeth M., Patti, Joseph M., McDevitt, Damien, Höök, Magnus, Jones, Dan B., Wilhelmus, Kirk R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97678/
https://ncbi.nlm.nih.gov/pubmed/10816547
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