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Nucleic acid fragmentation on the millisecond timescale using a conventional X-ray rotating anode source: application to protein–DNA footprinting

Nucleic acid fragmentation (footprinting) by ·OH radicals is used often as a tool to probe nucleic acid structure and nucleic acid–protein interactions. This method has proven valuable because it provides structural information with single base pair resolution. Recent developments in the field intro...

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Main Authors: Henn, Arnon, Halfon, Jacob, Kela, Itai, Orion, Itzhak, Sagi, Irit
格式: Artigo
語言:Inglês
出版: Oxford University Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC97631/
https://ncbi.nlm.nih.gov/pubmed/11812859
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