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Nucleic acid fragmentation on the millisecond timescale using a conventional X-ray rotating anode source: application to protein–DNA footprinting

Nucleic acid fragmentation (footprinting) by ·OH radicals is used often as a tool to probe nucleic acid structure and nucleic acid–protein interactions. This method has proven valuable because it provides structural information with single base pair resolution. Recent developments in the field intro...

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Detalhes bibliográficos
Main Authors: Henn, Arnon, Halfon, Jacob, Kela, Itai, Orion, Itzhak, Sagi, Irit
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97631/
https://ncbi.nlm.nih.gov/pubmed/11812859
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