A Subdominant CD8(+) Cytotoxic T Lymphocyte (CTL) Epitope from the Plasmodium yoelii Circumsporozoite Protein Induces CTLs That Eliminate Infected Hepatocytes from Culture

Previous studies indicated that the Plasmodium yoelii circumsporozoite protein (PyCSP) 57–70 region elicits T cells capable of eliminating infected hepatocytes in vitro. Herein, we report that the PyCSP58–67 sequence contains an H-2(d) binding motif, which binds purified K(d) molecules in vitro with...

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Main Authors: Franke, Eileen D., Sette, Alessandro, Sacci, John, Southwood, Scott, Corradin, Giampietro, Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC97612/
https://ncbi.nlm.nih.gov/pubmed/10816491
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