Effective inhibition of herpes simplex virus 1 gene expression and growth by engineered RNase P ribozyme

Using an in vitro selection procedure, we have previously isolated ribonuclease P (RNase P) ribozyme variants that efficiently cleave an mRNA sequence in vitro. In this study, an M1GS RNA variant was used to target the mRNA encoding human herpes simplex virus 1 (HSV-1) major transcription activator...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Trang, Phong, Lee, Jarone, Kilani, Ahmed F., Kim, Joe, Liu, Fenyong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11812839/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.24.5071
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