Immunization of Mice with Combinations of Pneumococcal Virulence Proteins Elicits Enhanced Protection against Challenge with Streptococcus pneumoniae

The vaccine potential of a combination of three pneumococcal virulence proteins was evaluated in an active-immunization–intraperitoneal-challenge model in BALB/c mice, using very high challenge doses of Streptococcus pneumoniae. The proteins evaluated were a genetic toxoid derivative of pneumolysin...

Celý popis

Podrobná bibliografie

Vydáno v:	Infect Immun
Hlavní autoři:	Ogunniyi, A. David, Folland, Rebekah L., Briles, David E., Hollingshead, Susan K., Paton, James C.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Microbial Immunity and Vaccines
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10769009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.3028-3033.2000
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!