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Immunogenicity and Efficacy in Aotus Monkeys of Four Recombinant Plasmodium falciparum Vaccines in Multiple Adjuvant Formulations Based on the 19-Kilodalton C Terminus of Merozoite Surface Protein 1

The immunogenicity and protective efficacy of four versions of recombinant C-terminal 19-kDa epidermal growth factor-like region of the major surface protein 1 (rMSP1(19)) of Plasmodium falciparum was studied in Aotus monkeys. Vaccination with each of the four rMSP1(19) constructs elicited high leve...

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Bibliografiske detaljer
Main Authors: Kumar, Sanjai, Collins, William, Egan, Andrea, Yadava, Anjali, Garraud, Olivier, Blackman, Michael J., Patino, Jose A. Guevara, Diggs, Carter, Kaslow, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97406/
https://ncbi.nlm.nih.gov/pubmed/10722622
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