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Immunogenicity and Efficacy in Aotus Monkeys of Four Recombinant Plasmodium falciparum Vaccines in Multiple Adjuvant Formulations Based on the 19-Kilodalton C Terminus of Merozoite Surface Protein 1

The immunogenicity and protective efficacy of four versions of recombinant C-terminal 19-kDa epidermal growth factor-like region of the major surface protein 1 (rMSP1(19)) of Plasmodium falciparum was studied in Aotus monkeys. Vaccination with each of the four rMSP1(19) constructs elicited high leve...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Kumar, Sanjai, Collins, William, Egan, Andrea, Yadava, Anjali, Garraud, Olivier, Blackman, Michael J., Patino, Jose A. Guevara, Diggs, Carter, Kaslow, David C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97406/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.4.2215-2223.2000
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