Clostridium difficile Recombinant Toxin A Repeating Units as a Carrier Protein for Conjugate Vaccines: Studies of Pneumococcal Type 14, Escherichia coli K1, and Shigella flexneri Type 2a Polysaccharides in Mice

Unlike the native protein, a nontoxic peptide (repeating unit of the native toxin designated rARU) from Clostridium difficile toxin A (CDTA) afforded an antigen that could be bound covalently to the surface polysaccharides of pneumococcus type 14, Shigella flexneri type 2a, and Escherichia coli K1....

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Pavliakova, Danka, Moncrief, J. Scott, Lyerly, David M., Schiffman, Gerald, Bryla, Dolores A., Robbins, John B., Schneerson, Rachel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97399/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.4.2161-2166.2000
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