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Interleukin-4 Receptor Alpha-Deficient BALB/c Mice Show an Unimpaired T Helper 2 Polarization in Response to Leishmania major Infection

We recently generated interleukin-4 (IL-4) receptor alpha-deficient (IL-4Rα(−/−)) BALB/c mice and showed evidence for a protective role of IL-13-mediated functions in leishmaniasis. In this study, we investigated the IL-4 expression and T helper 2 (Th2) development in Leishmania major-infected IL-4R...

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Autors principals: Mohrs, Markus, Holscher, Christoph, Brombacher, Frank
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97347/
https://ncbi.nlm.nih.gov/pubmed/10722563
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