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Construction and Characterization of a Salmonella enterica Serovar Typhimurium Clone Expressing a Salivary Adhesin of Streptococcus mutans under Control of the Anaerobically Inducible nirB Promoter

Attenuated Salmonella enterica serovar Typhimurium has been used for targeted delivery of recombinant antigens to the gut-associated lymphoid tissues. One potential problem associated with this vaccine approach is the likelihood of in vivo instability of the plasmid constructs caused by constitutive...

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Autores principales: Huang, Yan, Hajishengallis, George, Michalek, Suzanne M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC97314/
https://ncbi.nlm.nih.gov/pubmed/10678973
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