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Mutation and Recombination in the Upstream Homology Box-Flanked ospE-Related Genes of the Lyme Disease Spirochetes Result in the Development of New Antigenic Variants during Infection

The ospE gene family of the Lyme disease spirochetes encodes a polymorphic group of immunogenic lipoproteins. The ospE genes are one of several gene families that are flanked by a highly conserved upstream sequence called the upstream homology box, or UHB, element. Earlier analyses in our lab demons...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sung, Shian Ying, McDowell, John V., Carlyon, Jason A., Marconi, Richard T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97285/
https://ncbi.nlm.nih.gov/pubmed/10678944
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