Mutation and Recombination in the Upstream Homology Box-Flanked ospE-Related Genes of the Lyme Disease Spirochetes Result in the Development of New Antigenic Variants during Infection

The ospE gene family of the Lyme disease spirochetes encodes a polymorphic group of immunogenic lipoproteins. The ospE genes are one of several gene families that are flanked by a highly conserved upstream sequence called the upstream homology box, or UHB, element. Earlier analyses in our lab demons...

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Publié dans:	Infect Immun
Auteurs principaux:	Sung, Shian Ying, McDowell, John V., Carlyon, Jason A., Marconi, Richard T.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Molecular and Cellular Pathogenesis
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10678944/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.3.1319-1327.2000
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