Induction of Necrosis in Human Neutrophils by Shigella flexneri Requires Type III Secretion, IpaB and IpaC Invasins, and Actin Polymerization

Infection by Shigella flexneri is characterized by infiltration of neutrophils in the intestinal mucosa and by a strong inflammatory reaction. Although neutrophils are constitutively programmed to die by apoptosis, we show that isolated human neutrophils undergo necrosis 2 h after infection with vir...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: François, Mathias, Le Cabec, Véronique, Dupont, Marie-Ange, Sansonetti, Philippe J., Maridonneau-Parini, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Molecular and Cellular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97281/
https://ncbi.nlm.nih.gov/pubmed/10678940
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky