Allele Substitution of the Streptokinase Gene Reduces the Nephritogenic Capacity of Group A Streptococcal Strain NZ131

To investigate the role of allelic variants of streptokinase in the pathogenesis of acute poststreptococcal glomerulonephritis (APSGN), site-specific integration plasmids were constructed, which contained either the non-nephritis-associated streptokinase gene (skc5) from the group C streptococcal st...

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Bibliografiska uppgifter
Huvudupphovsmän: Nordstrand, Annika, McShan, W. Michael, Ferretti, Joseph J., Holm, Stig E., Norgren, Mari
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Bacterial Infections
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC97243/
https://ncbi.nlm.nih.gov/pubmed/10678902
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