Allele Substitution of the Streptokinase Gene Reduces the Nephritogenic Capacity of Group A Streptococcal Strain NZ131

To investigate the role of allelic variants of streptokinase in the pathogenesis of acute poststreptococcal glomerulonephritis (APSGN), site-specific integration plasmids were constructed, which contained either the non-nephritis-associated streptokinase gene (skc5) from the group C streptococcal st...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Nordstrand, Annika, McShan, W. Michael, Ferretti, Joseph J., Holm, Stig E., Norgren, Mari
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Bacterial Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10678902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.3.1019-1025.2000
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