Comparison of the Roles of Calcineurin in Physiology and Virulence in Serotype D and Serotype A Strains of Cryptococcus neoformans

The calcineurin gene was cloned and disrupted in serotype D strains of Cryptococcus neoformans. Serotype A and serotype D calcineurin mutants were inviable at 37°C and avirulent in mice, whereas only serotype A mutants were cation stress sensitive. Thus, calcineurin plays conserved and divergent rol...

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Bibliografische gegevens

Gepubliceerd in:	Infect Immun
Hoofdauteurs:	Cruz, M. Cristina, Sia, Rey A. L., Olson, Michael, Cox, Gary M., Heitman, Joseph
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2000
Onderwerpen:	Fungal and Parasitic Infections
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97236/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.982-985.2000
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