Matrix Metalloproteinases Contribute to Brain Damage in Experimental Pneumococcal Meningitis

The present study was performed to evaluate the role of matrix metalloproteinases (MMP) in the pathogenesis of the inflammatory reaction and the development of neuronal injury in a rat model of bacterial meningitis. mRNA encoding specific MMPs (MMP-3, MMP-7, MMP-8, and MMP-9) and the inflammatory cy...

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Pubblicato in:	Infect Immun
Autori principali:	Leib, Stephen L., Leppert, David, Clements, John, Täuber, Martin G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Bacterial Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.615-620.2000
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