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Matrix Metalloproteinases Contribute to Brain Damage in Experimental Pneumococcal Meningitis

The present study was performed to evaluate the role of matrix metalloproteinases (MMP) in the pathogenesis of the inflammatory reaction and the development of neuronal injury in a rat model of bacterial meningitis. mRNA encoding specific MMPs (MMP-3, MMP-7, MMP-8, and MMP-9) and the inflammatory cy...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Leib, Stephen L., Leppert, David, Clements, John, Täuber, Martin G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97183/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639424/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.615-620.2000
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