Construction and Characterization of an Effector Strain of Streptococcus mutans for Replacement Therapy of Dental Caries

An effector strain has been constructed for use in the replacement therapy of dental caries. Recombinant DNA methods were used to make the Streptococcus mutans supercolonizing strain, JH1140, lactate dehydrogenase deficient by deleting virtually all of the ldh open reading frame (ORF). To compensate...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Hillman, J. D., Brooks, T. A., Michalek, S. M., Harmon, C. C., Snoep, J. L., van der Weijden, C. C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Bacterial Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.543-549.2000
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