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Construction and Characterization of an Effector Strain of Streptococcus mutans for Replacement Therapy of Dental Caries

An effector strain has been constructed for use in the replacement therapy of dental caries. Recombinant DNA methods were used to make the Streptococcus mutans supercolonizing strain, JH1140, lactate dehydrogenase deficient by deleting virtually all of the ldh open reading frame (ORF). To compensate...

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Hlavní autoři: Hillman, J. D., Brooks, T. A., Michalek, S. M., Harmon, C. C., Snoep, J. L., van der Weijden, C. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97174/
https://ncbi.nlm.nih.gov/pubmed/10639415
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