Construction and Characterization of an Effector Strain of Streptococcus mutans for Replacement Therapy of Dental Caries

An effector strain has been constructed for use in the replacement therapy of dental caries. Recombinant DNA methods were used to make the Streptococcus mutans supercolonizing strain, JH1140, lactate dehydrogenase deficient by deleting virtually all of the ldh open reading frame (ORF). To compensate...

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Autors principals: Hillman, J. D., Brooks, T. A., Michalek, S. M., Harmon, C. C., Snoep, J. L., van der Weijden, C. C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Bacterial Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97174/
https://ncbi.nlm.nih.gov/pubmed/10639415
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