Construction and Characterization of an Effector Strain of Streptococcus mutans for Replacement Therapy of Dental Caries

An effector strain has been constructed for use in the replacement therapy of dental caries. Recombinant DNA methods were used to make the Streptococcus mutans supercolonizing strain, JH1140, lactate dehydrogenase deficient by deleting virtually all of the ldh open reading frame (ORF). To compensate...

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Библиографические подробности

Опубликовано в::	Infect Immun
Главные авторы:	Hillman, J. D., Brooks, T. A., Michalek, S. M., Harmon, C. C., Snoep, J. L., van der Weijden, C. C.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2000
Предметы:	Bacterial Infections
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.543-549.2000
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