Syntheses and Immunologic Properties of Escherichia coli O157 O-Specific Polysaccharide and Shiga Toxin 1 B Subunit Conjugates in Mice

Escherichia coli O157 is the major cause of diarrhea-associated hemolytic uremic syndrome (HUS). Strains causing HUS contain either Shiga toxin 1 (Stx1) or Stx2, or both. In adult volunteers, conjugate vaccines of detoxified lipopolysaccharide (LPS) elicited bactericidal antibodies to E. coli O157....

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Konadu, Edward, Donohue-Rolfe, Arthur, Calderwood, Stephen B., Pozsgay, Vince, Shiloach, Joseph, Robbins, John B., Szu, Shousun C.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1999
Subjects:	Microbial Immunity and Vaccines
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10531288/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.11.6191-6193.1999
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