Syntheses and Immunologic Properties of Escherichia coli O157 O-Specific Polysaccharide and Shiga Toxin 1 B Subunit Conjugates in Mice

Escherichia coli O157 is the major cause of diarrhea-associated hemolytic uremic syndrome (HUS). Strains causing HUS contain either Shiga toxin 1 (Stx1) or Stx2, or both. In adult volunteers, conjugate vaccines of detoxified lipopolysaccharide (LPS) elicited bactericidal antibodies to E. coli O157....

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Detalhes bibliográficos
Main Authors: Konadu, Edward, Donohue-Rolfe, Arthur, Calderwood, Stephen B., Pozsgay, Vince, Shiloach, Joseph, Robbins, John B., Szu, Shousun C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97014/
https://ncbi.nlm.nih.gov/pubmed/10531288
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