Pseudomonas aeruginosa Quorum-Sensing Signal Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone Inhibits Expression of P2Y Receptors in Cystic Fibrosis Tracheal Gland Cells

ATP and UTP have been proposed for use as therapeutic treatment of the abnormal ion transport in the airway epithelium in cystic fibrosis (CF), the most characteristic feature of which is permanent infection by Pseudomonas aeruginosa. As for diverse gram-negative bacteria, this pathogenic bacterium...

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Main Authors: Saleh, A., Figarella, C., Kammouni, W., Marchand-Pinatel, S., Lazdunski, A., Tubul, A., Brun, P., Merten, M. D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Molecular and Cellular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96855/
https://ncbi.nlm.nih.gov/pubmed/10496880
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