Molecular and Idiotypic Analyses of the Antibody Response to Cryptococcus neoformans Glucuronoxylomannan-Protein Conjugate Vaccine in Autoimmune and Nonautoimmune Mice

The antibody response to Cryptococcus neoformans capsular glucuronoxylomannan (GXM) in BALB/c mice frequently expresses the 2H1 idiotype (Id) and is restricted in variable gene usage. This study examined the immunogenicity of GXM-protein conjugates, V (variable)-region usage, and 2H1 Id expression i...

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Main Authors: Nussbaum, Gabriel, Anandasabapathy, Sharmila, Mukherjee, Jean, Fan, Manxia, Casadevall, Arturo, Scharff, Matthew D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC96766/
https://ncbi.nlm.nih.gov/pubmed/10456888
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