Molecular and Idiotypic Analyses of the Antibody Response to Cryptococcus neoformans Glucuronoxylomannan-Protein Conjugate Vaccine in Autoimmune and Nonautoimmune Mice

The antibody response to Cryptococcus neoformans capsular glucuronoxylomannan (GXM) in BALB/c mice frequently expresses the 2H1 idiotype (Id) and is restricted in variable gene usage. This study examined the immunogenicity of GXM-protein conjugates, V (variable)-region usage, and 2H1 Id expression i...

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Vydáno v:	Infect Immun
Hlavní autoři:	Nussbaum, Gabriel, Anandasabapathy, Sharmila, Mukherjee, Jean, Fan, Manxia, Casadevall, Arturo, Scharff, Matthew D.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Fungal and Parasitic Infections
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96766/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10456888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.9.4469-4476.1999
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