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Intranasal Immunization with Heat-Inactivated Streptococcus pneumoniae Protects Mice against Systemic Pneumococcal Infection

In order to study the mucosal and serum antibody response to polysaccharide-encapsulated bacteria in mice, a preparation of heat-inactivated Streptococcus pneumoniae type 4 was administered, with and without cholera toxin, at various mucosal sites. It appeared that intranasal immunization of nonanes...

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Bibliografiska uppgifter
Huvudupphovsmän: Hvalbye, Benedicte K. R., Aaberge, Ingeborg S., Løvik, Martinus, Haneberg, Bjørn
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC96747/
https://ncbi.nlm.nih.gov/pubmed/10456869
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