Intranasal Vaccination with Pneumococcal Surface Protein A and Interleukin-12 Augments Antibody-Mediated Opsonization and Protective Immunity against Streptococcus pneumoniae Infection

Streptococcus pneumoniae is a major pathogen in humans that enters the host primarily through the respiratory tract. Targeting mucosal surfaces directly may therefore be an optimal approach for vaccination to prevent bacterial colonization and invasive disease. We have previously demonstrated the ef...

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Detalhes bibliográficos
Main Authors: Arulanandam, Bernard P., Lynch, Joyce M., Briles, David E., Hollingshead, Susan, Metzger, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100048/
https://ncbi.nlm.nih.gov/pubmed/11598043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.6718-6724.2001
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