Avirulence of Candida albicans CaHK1 Mutants in a Murine Model of Hematogenously Disseminated Candidiasis

Deletion of both alleles of the Candida albicans CaHK1 gene, which causes cells to flocculate when grown at pH 7.5, a pH comparable to that of mammalian blood, abolishes the ability of the yeast to establish a successful infection in a murine model of hematogenously disseminated candidiasis. Within...

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Bibliographic Details
Main Authors: Calera, José Antonio, Zhao, Xiao-Jiong, De Bernardis, Flavia, Sheridan, Michael, Calderone, Richard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC96739/
https://ncbi.nlm.nih.gov/pubmed/10417206
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