Avirulence of Candida albicans CaHK1 Mutants in a Murine Model of Hematogenously Disseminated Candidiasis

Deletion of both alleles of the Candida albicans CaHK1 gene, which causes cells to flocculate when grown at pH 7.5, a pH comparable to that of mammalian blood, abolishes the ability of the yeast to establish a successful infection in a murine model of hematogenously disseminated candidiasis. Within...

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Publié dans:	Infect Immun
Auteurs principaux:	Calera, José Antonio, Zhao, Xiao-Jiong, De Bernardis, Flavia, Sheridan, Michael, Calderone, Richard
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1999
Sujets:	Fungal and Parasitic Infections
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10417206/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.8.4280-4284.1999
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