Intranasal Immunization with Pneumococcal Polysaccharide Conjugate Vaccines Protects Mice against Invasive Pneumococcal Infections

Host defenses against Streptococcus pneumoniae depend largely on opsonophagocytosis mediated by antibodies and complement. Since pneumococcus is a respiratory pathogen, mucosal immune responses may play a significant role in the defense against pneumococcal infections. Thus, mucosal vaccination may...

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Bibliographic Details
Main Authors: Jakobsen, Håvard, Saeland, Eiríkur, Gizurarson, Sveinbjörn, Schulz, Dominique, Jónsdóttir, Ingileif
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC96716/
https://ncbi.nlm.nih.gov/pubmed/10417183
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