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Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells

Telomerase is a reverse transcriptase that adds telomeric repeats to chromosomal ends. In most normal human somatic cells, telomerase is repressed and telomeres progressively shorten, leading to limited proliferative life-span. Telomerase reactivation is associated with cellular immortalization and...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Yi, Xiaoming, Shay, Jerry W., Wright, Woodring E.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96692/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.23.4818
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