Characterization of a Haemophilus ducreyi Mutant Deficient in Expression of Cytolethal Distending Toxin

Haemophilus ducreyi expresses a soluble cytolethal distending toxin (CDT) that kills HeLa, HEp-2, and other human epithelial cells in vitro. H. ducreyi CDT activity is encoded by a three-gene cluster (cdtABC), and antibody to the cdtC gene product can neutralize CDT activity in vitro (L. D. Cope, S....

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Autori principali: Stevens, Marla K., Latimer, Jo L., Lumbley, Sheryl R., Ward, Christine K., Cope, Leslie D., Lagergard, Teresa, Hansen, Eric J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
Soggetti:
Molecular and Cellular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC96670/
https://ncbi.nlm.nih.gov/pubmed/10417154
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