Characterization of a Haemophilus ducreyi Mutant Deficient in Expression of Cytolethal Distending Toxin

Haemophilus ducreyi expresses a soluble cytolethal distending toxin (CDT) that kills HeLa, HEp-2, and other human epithelial cells in vitro. H. ducreyi CDT activity is encoded by a three-gene cluster (cdtABC), and antibody to the cdtC gene product can neutralize CDT activity in vitro (L. D. Cope, S....

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Stevens, Marla K., Latimer, Jo L., Lumbley, Sheryl R., Ward, Christine K., Cope, Leslie D., Lagergard, Teresa, Hansen, Eric J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Molecular and Cellular Pathogenesis
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96670/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10417154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.8.3900-3908.1999
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