Genetic Characterization of a Tn5-Disrupted Glycosyltransferase Gene Homolog in Brucella abortus and Its Effect on Lipopolysaccharide Composition and Virulence

We constructed a rough mutant of Brucella abortus 2308 by transposon (Tn5) mutagenesis. Neither whole cells nor extracted lipopolysaccharide (LPS) from this mutant, designated RA1, reacted with a Brucella O-side-chain-specific monoclonal antibody (MAb), Bru-38, indicating the absence of O-side-chain...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	McQuiston, J. R., Vemulapalli, R., Inzana, T. J., Schurig, G. G., Sriranganathan, N., Fritzinger, D., Hadfield, T. L., Warren, R. A., Snellings, N., Hoover, D., Halling, S. M., Boyle, S. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10417145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.8.3830-3835.1999
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