Interleukin-12 Enhances Antifungal Activity of Human Mononuclear Phagocytes against Aspergillus fumigatus: Implications for a Gamma Interferon-Independent Pathway

The potential of recombinant human interleukin-12 (IL-12) to enhance the capacity of human monocytes (MNC) to elicit an oxidative burst and damage hyphae of Aspergillus fumigatus was investigated. Incubation of peripheral blood mononuclear cells (PBMC) from healthy adults with 10 to 100 ng of IL-12/...

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Autores principales: Roilides, Emmanuel, Tsaparidou, Sevasti, Kadiltsoglou, Isaac, Sein, Tin, Walsh, Thomas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC96619/
https://ncbi.nlm.nih.gov/pubmed/10338518
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