Interleukin-12 Enhances Antifungal Activity of Human Mononuclear Phagocytes against Aspergillus fumigatus: Implications for a Gamma Interferon-Independent Pathway

The potential of recombinant human interleukin-12 (IL-12) to enhance the capacity of human monocytes (MNC) to elicit an oxidative burst and damage hyphae of Aspergillus fumigatus was investigated. Incubation of peripheral blood mononuclear cells (PBMC) from healthy adults with 10 to 100 ng of IL-12/...

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Main Authors: Roilides, Emmanuel, Tsaparidou, Sevasti, Kadiltsoglou, Isaac, Sein, Tin, Walsh, Thomas J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Fungal and Parasitic Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC96619/
https://ncbi.nlm.nih.gov/pubmed/10338518
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